Report error Found 105 Enz. Inhib. hit(s) for PDB: 3WZE
Displayed 1 to 50 (of 105 total ) | Next | Last >>
Affinity DataKi: 0.0210nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by activity based 100 fold dilution assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.0600nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by ligand displacement based enzyme-inhibitor dilution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 preincubated for 120 mins in presence of ATP by AlphaScreen analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 1 hr by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:An in vitro kinase assay was performed to evaluate the kinase suppression activity of the most promising cytotoxic candidates 4b, 4j against four dif...More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ATP measured luminescence by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of VEGFR2 (unknown origin) using Poly E4Y1 substrate after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of KDR (unknown origin) incubated for 1 hr assessed as luminescence changes using ATP by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 expressed in Sf9 insect cells after 120 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of VEGFR-2 (unknown origin) incubated for 60 mins by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of VEGFR-2 (unknown origin) incubated for 45 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human N-terminal His-tagged phosphorylated VEGFR2 preincubated for 120 mins in presence of ATP by AlphaScreen analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant GST-fused VEGFR2 kinase domain transphosphorylation expressed in baculovirus expression system using poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of VEGF-induced human VEGFR2 autophosphorylation transfected in CHO cells by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In this experiment, the inhibitory effects of small molecule inhibitors on 17 kinases were examined by using fluorescent microfluidic mobility shift ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...More data for this Ligand-Target Pair
Affinity DataIC50: 11.1nMT: 2°CAssay Description:Experimental Procedures(1) Kinase reaction substrate Poly(Glu, Tyr, 4:1) was diluted to 20 g/ml with potassium ion-free PBS, and enzyme labeled plate...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged recombinant human VEGFR2 expressed in Sf9 cells by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of FLK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression system by Z'-Lyte ass...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR2 (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 10 mins by Global fit analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant VEGFR2 using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 min...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 in presence of ATP measured without preincubation by AlphaScreen analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate measured after 1 hr in presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human VEGFR-2 after 2.5 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding affinity to VEGFR2 (unknown origin) by proteros reporter displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of VEGFR2 (unknown origin) using Poly (Glu, Tyr) 4:1 as substrate preincubated with substrate followed by enzyme challenge for 1 hr by ELI...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 kinase domain (V789 to V1356) (unknown origin) expressed in insect Sf9 cells using polyGlu4:Tyr peptide a...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of VEGFR2 (unknown origin) using biotin substrate incubated for 1 hr by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of human VEGFR2 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by kinase glo detection reagent based assayMore data for this Ligand-Target Pair
Affinity DataKd: 59nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 59nMAssay Description:Binding constant for VEGFR2 kinase domainMore data for this Ligand-Target Pair