Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4A03
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology and Science-Pilani

Curated by ChEMBL
LigandPNGBDBM50181153(FR-900098 | 3-(N-hydroxyformamido)propylphosphonic...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR in presence of NADPH by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology and Science-Pilani

Curated by ChEMBL
LigandPNGBDBM50181153(FR-900098 | 3-(N-hydroxyformamido)propylphosphonic...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology and Science-Pilani

Curated by ChEMBL
LigandPNGBDBM50181153(FR-900098 | 3-(N-hydroxyformamido)propylphosphonic...)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DxrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology and Science-Pilani

Curated by ChEMBL
LigandPNGBDBM50181153(FR-900098 | 3-(N-hydroxyformamido)propylphosphonic...)
Affinity DataKi:  130nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and MgCl2 as cofactor preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)