Report error Found 2 Enz. Inhib. hit(s) for PDB: 4A55
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Mirati Therapeutics
Curated by ChEMBL
Mirati Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 20 mins in presence of gamma-32P-ATP by TLC analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Mirati Therapeutics
Curated by ChEMBL
Mirati Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kalpha expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as ...More data for this Ligand-Target Pair