Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 4DBS
TargetAldo-keto reductase family 1 member C3(Human)
Perelman School of Medicine University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant AKR1C3 assessed as enzyme catalyzed oxidation of S-tetralol by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
Perelman School of Medicine University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 86nMAssay Description:Inhibition of human AKR1C3 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Perelman School of Medicine University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 8.17E+3nMAssay Description:Inhibition of recombinant AKR1C2 assessed as enzyme catalyzed oxidation of S-tetralol by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
Perelman School of Medicine University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of recombinant AKR1C1 assessed as enzyme catalyzed oxidation of S-tetralol by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Perelman School of Medicine University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of human AKR1C2 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
Perelman School of Medicine University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50382163(CHEMBL2023820)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human AKR1C1 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)