Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 4DBU
TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 62nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 62nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 1.50E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 2.27E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of recombinant AKR1C1 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of recombinant AKR1C1 assessed as enzyme catalyzed oxidation of S-tetralol by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)