Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4DEB
TargetAurora kinase A(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM209951(US9249124, RK2-017-01)
Affinity DataIC50: 226nMAssay Description:The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details
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PDB3D3D Structure (crystal)
TargetAurora kinase A(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM209951(US9249124, RK2-017-01)
Affinity DataIC50: 372nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)