Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4E3H
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26190(CHEMBL537 | benzene-1,4-diol | Hydroquinone, HQ | ...)
Affinity DataKi:  90nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26190(CHEMBL537 | benzene-1,4-diol | Hydroquinone, HQ | ...)
Affinity DataKi:  90nM ΔG°:  -40.2kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26190(CHEMBL537 | benzene-1,4-diol | Hydroquinone, HQ | ...)
Affinity DataKi:  100nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)