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Found
2
Enz. Inhib. hit(s) for PDB:
4E4L
Target
Tyrosine-protein kinase JAK1
(Human)
Argenta Discovery
Curated by
ChEMBL
Ligand
BDBM50392018
(CHEMBL2152409)
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Affinity Data
Ki: 1.70nM
Assay Description:
Inhibition of JAK1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
5/17/2013
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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Target
Tyrosine-protein kinase JAK1
(Human)
Argenta Discovery
Curated by
ChEMBL
Ligand
BDBM50392018
(CHEMBL2152409)
Copy SMILES
Copy InChI
Affinity Data
EC50: 210nM
Assay Description:
Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL2-induced STAT3 phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
5/17/2013
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
Copy reaction URL