Report error Found 12 Enz. Inhib. hit(s) for PDB: 4EQC
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PAK1 (unknown origin) by ATP-kinaseGlo assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human PAK1 by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
Affinity DataIC50: 12.8nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human PAK2 by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of PAK1 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of PAK2 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human PAK3 by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 19.3nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of PAK3 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of PAK1 phosphorylation in human MCF10A cellsMore data for this Ligand-Target Pair