Affinity DataKd: 8nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 43nMAssay Description:In vitro reversal of vecuronium-induced neuromuscular block in guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory effect on rat AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of rat cortex homogenate acetylcholinesterase using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of acetylcholinesterase (AChE) of human red blood cell (type XIII) by modified radiometric AChE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of AChE (unknown origin) incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of bovine acetylcholinesterase using acetylcholine iodide as substrate incubated for 20 mins prior to substrate addition measured after 3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate incubated for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of AChE in mouse cerebral cortex using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 5 mins prior to substrate addition meas...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AChE in mouse brain homogenate using acetylthiocholine as substrate preincubated for 300 secs followed by substrate addition by Ellman'...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by U...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibitory concentration in vitro and ex vivo for anti-AChE activity in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of rat cortex AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase (AChE) in bovine brainMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human AChE using ATCI as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins by spectro...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant AChE preincubated for 5 mins followed by acetylthiocholine iodide substrate addition measured after 5 mins by Ellman'...More data for this Ligand-Target Pair
Affinity DataIC50: 6.16nMpH: 8.0 T: 2°CAssay Description:Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate by UV-visible spectrophotometric Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate peincubated for 5 mins followed by substrate addition by DTNB-reagen...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of AchE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant AChE in human erythrocytes using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of AChE in rat cortex preincubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:The potential of the compounds of the present invention to inhibit acetylcholinesterase and butyrylcholinesterase enzymes were tested according to th...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase (AChE) in bovine erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase (AChE) in human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide substrate incubated for 15 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.12nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
