Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 4FKI
TargetCyclin-dependent kinase 2(Human)
Institute of Chemical Biology (Csir)

Curated by ChEMBL
LigandPNGBDBM7157(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-trifluorome...)
Affinity DataIC50: 67nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Pharmacia Italia

LigandPNGBDBM7157(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-trifluorome...)
Affinity DataIC50: 67nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Pharmacia Italia

LigandPNGBDBM7157(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-trifluorome...)
Affinity DataKd:  463nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Institute of Chemical Biology (Csir)

Curated by ChEMBL
LigandPNGBDBM7157(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-trifluorome...)
Affinity DataKd:  6.89E+3nMpH: 7.5 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Institute of Chemical Biology (Csir)

Curated by ChEMBL
LigandPNGBDBM7157(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-trifluorome...)
Affinity DataKd:  5.83E+4nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)