Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4GQ0
TargetAldo-keto reductase family 1 member B10(Human)
Institut De Ge��Ne��Tique Et De Biologie Mole��Culaire Et Cellulaire

LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
Institut De Ge��Ne��Tique Et De Biologie Mole��Culaire Et Cellulaire

LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
Institut De Ge��Ne��Tique Et De Biologie Mole��Culaire Et Cellulaire

LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 390nMAssay Description:Inhibition of N-terminal His-tagged human AKR1B10 expressed in Escherichia coli BL21 (Condon Plus) competent cells using pyridine-3-aldehydenone as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B10(Human)
Institut De Ge��Ne��Tique Et De Biologie Mole��Culaire Et Cellulaire

LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataKi:  46nMAssay Description:Mixed-type inhibition at human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as inhibition of NADP+ link...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)