Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4GRQ
TargetMacrophage migration inhibitory factor(Human)
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50240404(CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMacrophage migration inhibitory factor(Human)
L2 Diagnostics

Curated by ChEMBL
LigandPNGBDBM50240404(CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...)
Affinity DataKi:  3.09E+4nMAssay Description:Non-competitive inhibition of recombinant human MIF assessed as inhibition constant using varying levels of p-hydroxyphenylpyruvate as substrate by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)