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Found
1
Enz. Inhib. hit(s) for PDB:
4I5I
Target
NAD-dependent protein deacetylase sirtuin-1
(Human)
Elixir Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50178775
((S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]in...)
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Affinity Data
IC50: 63nM
Assay Description:
Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay
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Target Info
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Ligand Info
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CHEMBL
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PC sid
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In Depth
Date in BDB:
11/10/2009
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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