Report error Found 4 Enz. Inhib. hit(s) for PDB: 4IE7
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity using m6A7-Broccoli RNA as substrate incubated for 3 mins under shaking condition and measu...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of ssDNA from FTO (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of ssDNA with ATTGTCA (m6A) CAGCAGA-FAM from human FTO measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair