Affinity DataKd: 79nMAssay Description:Binding affinity to TBK1 in human HEK293/K562/placenta/HepG2 cell lysate mixture incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding affinity to phosphorylated TBK1 in calyculin A stimulated human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataKd: 251nMAssay Description:Binding affinity to TBK1 in human Ramos cell lysate incubated for 45 mins by kinobeads based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of TBK1 (unknown origin) incubated for 1 hr in presence of ATP by FRET based Z'-Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 357nMAssay Description:Inhibition of TBK1 in human THP1-Blue ISG cells by measuring SEAP gene expression incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair

3D Structure (crystal)