Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4J0Z
TargetBeta-secretase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50432604(CHEMBL2347186)
Affinity DataIC50: 25nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50432604(CHEMBL2347186)
Affinity DataIC50: 77nMAssay Description:Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)