Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 4J51
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataKi:  110nMAssay Description:Competitive inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50: 250nMAssay Description:Reversible inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50: 259nMAssay Description:Reversible inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50: 259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50: 259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)