Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4J71
TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM26979(CHEMBL69710 | chloride ion | Cl- | SODIUM CHLORIDE...)
Affinity DataIC50: 6.53E+3nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated GS1 peptide as substrate after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50192839(CHEMBL3984982)
Affinity DataKd:  6.00E+5nMAssay Description:Binding affinity to GSK-3 beta (unknown origin) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM26979(CHEMBL69710 | chloride ion | Cl- | SODIUM CHLORIDE...)
Affinity DataEC50: >3.00E+6nMAssay Description:Effective concentration of compound against glycogen synthase kinase-3 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)