Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4JR5
TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435378(CHEMBL1586371)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged human NAMPT expressed in Escherichia coli BL21 CodonPlus (DE3)-RIPL cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435378(CHEMBL1586371)
Affinity DataIC50: 7nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435378(CHEMBL1586371)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435378(CHEMBL1586371)
Affinity DataIC50: 61nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)