Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4K9T
TargetCytochrome P450 3A4(Human)
University of California Irvine

LigandPNGBDBM119125(GS4)
Affinity DataKd:  1.50E+3nMpH: 7.4Assay Description:Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

LigandPNGBDBM119125(GS4)
Affinity DataKd:  1.31E+4nMpH: 7.4Assay Description:Ligand binidng to CYP3A4 was monitored in 50 mM phosphate (pH 7.4) containing 20% glycerol and 1 mM DTT. The protein was titrated with small aliquots...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

LigandPNGBDBM119125(GS4)
Affinity DataIC50: 1.50E+4nMAssay Description:The inhibitory potency of compounds GS4-GS8 on the 7-benzyloxy-4-(trifluoromethyl)coumarin hydroxylase activity of CYP3A4 was evaluated according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)