Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 4L19
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataIC50: 400nMAssay Description:Inhibition of full-length recombinant human MMP-13 assessed as bovine type-2 collagen hydrolysis after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataKi:  800nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using varying levels of fTHP-15 as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataKi:  824nMAssay Description:Noncompetitive inhibition of human full length recombinant MMP13 using triple-helical fTHP-15 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataIC50: 2.40E+3nMAssay Description:Non-competitive inhibition of full-length recombinant human MMP-13 assessed as fTHP-15 substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)