Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4LCE
TargetC-terminal-binding protein 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM154571(4-Methylthio 2-oxobutyric acid (MTOB))
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-terminal-binding protein 1(Human)
University of Massachusetts Medical School

LigandPNGBDBM154571(4-Methylthio 2-oxobutyric acid (MTOB))
Affinity DataKd:  1.26E+6nMpH: 7.5Assay Description:Purified CtBP2 was dialyzed overnight against 500 mL of 50 mM glycylglycine at pH 8.5, 300 mM NaCl, 1 mM EDTA, and 2 mM TCEP, with or without 1.5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-terminal-binding protein 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM154571(4-Methylthio 2-oxobutyric acid (MTOB))
Affinity DataKd:  2.96E+6nMpH: 8.5Assay Description:Purified CtBP2 was dialyzed overnight against 500 mL of 50 mM glycylglycine at pH 8.5, 300 mM NaCl, 1 mM EDTA, and 2 mM TCEP, with or without 1.5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)