Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4LL0
TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31826(CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [668-1210](Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31826(CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...)
Affinity DataIC50: 0.430nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31826(CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...)
Affinity DataIC50: 2.62nMAssay Description:Inhibition of recombinant EGFR by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [696-1210,T790M](Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31826(CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...)
Affinity DataIC50: 360nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)