Affinity DataIC50: 3.90nMAssay Description:Inhibition of C-terminal His-tagged human full-length NAMPT expressed in Escherichia coli Rosetta DE3 using nicotinamide as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of N-terminal 6His-tagged human NAMPT (unknown origin) expressed in Escherichia coli Rosetta (DE) cells incubated for 1 hr by bradford ass...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate pre-treated for 15 mins followed by substrate addition incubated for 60 mins by fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human full length C-terminal His6-tagged NAMPT expressed in Escherichia coli Rosetta (DE3) cells using nicotinamide as substrate incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of NAMPT in human A2780 cells assessed as decrease in cell viability after 72 hrs by SRB assayMore data for this Ligand-Target Pair

3D Structure (crystal)