Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) for PDB: 4NF5
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  280nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  390nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  460nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  2.80E+3nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University Walk

Curated by ChEMBL
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  5.90E+3nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2D(Rat)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  2.10E+4nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)