Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4NFN
TargetTau-tubulin kinase 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50602885(CHEMBL5193906)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant catalytic domain TTBK1 (1 to 415 residues) extracted from Escherichia coli BL21 (DE3) incubated for 1 hr by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTau-tubulin kinase 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50602885(CHEMBL5193906)
Affinity DataIC50: 120nMAssay Description:Inhibition of TTBK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTau-tubulin kinase 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50602885(CHEMBL5193906)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)