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Found
1
Enz. Inhib. hit(s) for PDB:
4NH8
Target
Heat shock protein HSP 90-beta
(Human)
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50445478
(CHEMBL3104858)
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Affinity Data
IC50: 30nM
Assay Description:
Inhibition of HSP90 in Huntington's disease patient derived fibroblasts assessed as reduction of mHtt level after 48 hrs by Western blot analysis
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Target Info
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KEGG
UniProtKB/SwissProt
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Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
Date in BDB:
2/6/2015
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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