Report error Found 6 Enz. Inhib. hit(s) for PDB: 4NIE
Affinity DataEC50: 7.80nMAssay Description:Agonist activity at APC-labeled RORgammat LBD (unknown origin) incubated for 1 hr in presence of europium labeled co-activator SRC1 by dual FRET assa...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 20nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inverse agonist activity at biotinylated human RORgammat expressed in Escherichia coli BL21 assessed as effect on recruitment of SRC1/2 after 1 hr by...More data for this Ligand-Target Pair
Affinity DataEC50: 99nMAssay Description:Agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as maximum activation incubated for 1 hr in presence of europium labeled co-a...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at human RORgammat LBD expressed in HEK293T cells assessed as increase in Gal4 reporter gene transcription measured after 16 to 20 h...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inverse agonist activity at biotinylated human RORgammat LBD expressed in Escherichia coli BL21 assessed as inhibition of SRC1 recruitment after 1 hr...More data for this Ligand-Target Pair