Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4NYJ
TargetSon of sevenless homolog 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280579(CHEMBL4169930)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280579(CHEMBL4169930)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human SOS1 mediated nucleotide exchange in presence of BODIPY-GDP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)