Report error Found 2 Enz. Inhib. hit(s) for PDB: 4NYJ
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human SOS1 mediated nucleotide exchange in presence of BODIPY-GDP by fluorescence based analysisMore data for this Ligand-Target Pair

3D Structure (crystal)