Report error Found 10 Enz. Inhib. hit(s) for PDB: 4O28
Affinity DataEC50: 1.10nMAssay Description:Inhibition of NAMPT in human PC3 cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 1.30nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of NAMPT in human A2780 cells assessed as decrease in cell viability after 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length C-terminal His6-tagged NAMPT expressed in Escherichia coli Rosetta (DE3) cells using nicotinamide as substrate incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-tagged NAMPT (unknown origin) expressed in Escherichia coli BL21 using nicotinamide as substrate preincubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The reaction was carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well plates. NAMPT protein was added to 1 B...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of rat NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant NAMPT (unknown origin) incubated for 60 mins by SpectraMax microplate reader analysisMore data for this Ligand-Target Pair