Affinity DataIC50: 10nMAssay Description:In vitro agonistic activity against human androgen receptor (hAR) expressed in CV-1 cells; not activeMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 11nMAssay Description:Binding affinity to Androgen receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]testosterone from androgen receptor in Sprague-Dawley rat prostate gland after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity for mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of [3H]-DHT binding to T877A androgen receptor of LNCaP cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [3H]testosterone from Sprague-Dawley rat AR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of wild type Androgen receptor (unknown origin) expressed in Freestyle293F cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [17-alpha-methyl-3H]-mibolerone from human androgen receptor expressed in HEK293 derived FreeStyle293F cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [17-alpha-methyl-3H]mibolerone from androgen receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]DHT from AR in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]-DHT from androgen receptor in human MDA-MB-453 cells after 90 mins by TopCount analysisMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition of [3H]DHT binding to androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Binding affinity for androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Displacement of [3H]DHT from androgen receptor of human MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nM ΔG°: -42.5kJ/mole IC50: 128nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 86.9nMAssay Description:Antagonist activity against pSG5-tagged human androgen receptor expressed in COS1 cells assessed as reduction in receptor-mediated transcriptional ac...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Displacement of [3H]R1881 from pSG5-tagged human androgen receptor expressed in COS1 cells assessed as relative binding inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Binding affinity for human androgen receptor transfected into mammalian COS-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Binding affinity for human androgen receptor in transiently-transfected COS-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Antagonist activity at Androgen receptor (unknown origin) in African green monkey COS-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Antagonist activity at androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone-induced transcriptional activity by re...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
Affinity DataKi: 151nMAssay Description:Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 151nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 151nM IC50: 162nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataEC50: 157nMAssay Description:In vitro antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Antagonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Antagonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Antagonist activity at human androgen receptor in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Antagonist activity at human wild type AR expressed in human MDA-MB-435 cells by transactivation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells assessed as inhibition of DHT-induced PSA expression by alkaline phosphatase repor...More data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Antagonist activity at human androgen receptor in MDA453 cells by alkaline phosphatase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of human androgen receptor of breast carcinoma MDA-453 cells in reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
