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Found
1
Enz. Inhib. hit(s) for PDB:
4P73
Target
Phenylalanine--tRNA ligase alpha/beta subunit
(Pseudomonas aeruginosa)
Astrazeneca R&D Boston
Ligand
BDBM231665
(1-(3-(4-(Pyridin-2-yl)piperazin-1-ylsulfonyl)pheny...)
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Affinity Data
IC50: 22nM
pH: 8.0
Assay Description:
Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...
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Target Info
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Ligand Info
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In Depth
Date in BDB:
6/9/2017
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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