Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 4TKF
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234919(CHEMBL1956162)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234919(CHEMBL1956162)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234919(CHEMBL1956162)
Affinity DataIC50: 56nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234919(CHEMBL1956162)
Affinity DataIC50: 343nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells using TACS-Sapphire a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50234919(CHEMBL1956162)
Affinity DataIC50: 347nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells using TACS-Sapphire a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)