Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4TQN
TargetCREB-binding protein(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148552(CHEMBL3770150)
Affinity DataKd:  670nMAssay Description:Competitive binding affinity to human His-tagged CREBBP expressed in T7 phage-infected Escherichia coli BL21(DE3) cells incubated for 1 hr by bromosc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148552(CHEMBL3770150)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human His-tagged CREBBP expressed in Escherichia coli BL21(DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148552(CHEMBL3770150)
Affinity DataKd:  770nMAssay Description:Competitive binding affinity to partial length human CREBBP expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148552(CHEMBL3770150)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)