Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4UH0
TargetNitric oxide synthase, brain(Rat)
Northwestern University

US Patent
LigandPNGBDBM152713(4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  35nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
Northwestern University

US Patent
LigandPNGBDBM152713(4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  35nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Human)
Northwestern University

US Patent
LigandPNGBDBM152713(4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  64nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent

TargetNitric oxide synthase, brain(Human)
Northwestern University

US Patent
LigandPNGBDBM152713(4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  64nMAssay Description:Inhibition of human recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed