Report error Found 24 Enz. Inhib. hit(s) for PDB: 4UND
Affinity DataIC50: 0.570nMAssay Description:Inhibition of recombinant human PARP1 using HRP as substrate by ELISA analysisMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.570nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human recombinant PARP-1 (662 to 1011 residues)More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to PARP1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 0.600nMAssay Description:Binding affinity to PARP1 (unknown origin) assessed as dissociation constant incubated for 30 mins by streptavidin pulldown based Western blot analys...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PARP1 (unknown origin) using NAD as substrate incubated for 1 minMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity to PARP1 (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.90nMAssay Description:Binding affinity to PARP1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Inhibition of human PARP-1 catalytic domain (662 to 1011 residues) expressed in Escherichia coli BL21(DE3) cells incubated for 0.5 hrs by fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminal 6His-6Lys-TEV tagged PARP1 full length expressed in pFastBac expression system incubated for 4 hrs by fluo...More data for this Ligand-Target Pair