Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4WLB
TargetNuclear receptor ROR-gamma(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50035886(CHEMBL3361065)
Affinity DataEC50:  520nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain expressed in bacterial expression system assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50035886(CHEMBL3361065)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)