Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4WUA
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataIC50: 83nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSRSF protein kinase 1(Mouse)
Sri International

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataKi:  890nMAssay Description:Inhibition of mouse His6-tagged SRPK1 expressed in Escherichia coli(BL21)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataIC50: 890nMAssay Description:Inhibition of SRPK1 (unknown origin) using SRSF1 Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH) as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataEC50:  2.36E+3nMAssay Description:Inhibition of C-terminal nLuc-fused SRPK1 (unknown origin) transfected in intact HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)