Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4X5Y
TargetMenin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454124(CHEMBL3780822)
Affinity DataKd:  9.30nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454124(CHEMBL3780822)
Affinity DataKd:  10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454124(CHEMBL3780822)
Affinity DataIC50: 15nMAssay Description:Displacement of FITC-MBM1 from full length human menin measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)