Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4YBS
TargetTranscription intermediary factor 1-alpha(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50150808(CHEMBL3774507 | US10702504, Compound C)
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50150808(CHEMBL3774507 | US10702504, Compound C)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50150808(CHEMBL3774507 | US10702504, Compound C)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)