Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 4YC9
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to recombinant human TRIM24-PHD/bromodomain expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells using biotinylated H3K23ac (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataKd:  31nMAssay Description:Binding affinity to recombinant human His-tagged TRIM24-PHD/bromodomain expressed in Escherichia coli strains BL21 (DE3) cells by isothermal titratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataEC50:  50nMAssay Description:Inhibition of Flag-tagged TRIM24-PHD/bromodomain (unknown origin) expressed in human HeLa cells for 2 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataIC50: 150nMAssay Description:Inhibition of TRIM24 (unknown origin) measured alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)