Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4YFI
TargetSerine/threonine-protein kinase TNNI3K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118389(CHEMBL3612641)
Affinity DataKd:  111nMAssay Description:Binding affinity to TNNI3K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase TNNI3K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118389(CHEMBL3612641)
Affinity DataIC50: 500nMAssay Description:Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase TNNI3K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118389(CHEMBL3612641)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)