Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4YND
TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095537(CHEMBL3590526 | US9598381, 1a (S enantiomer))
Affinity DataIC50: 2.80nMAssay Description:Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095537(CHEMBL3590526 | US9598381, 1a (S enantiomer))
Affinity DataIC50: 23nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)