Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4ZQL
TargetTranscription intermediary factor 1-alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148478(CHEMBL3769965 | US10702504, Compound A)
Affinity DataKd:  222nMAssay Description:Binding affinity to N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by iso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148478(CHEMBL3769965 | US10702504, Compound A)
Affinity DataIC50: 430nMAssay Description:Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Scr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription intermediary factor 1-alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148478(CHEMBL3769965 | US10702504, Compound A)
Affinity DataIC50: 750nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)