Report error Found 2 Enz. Inhib. hit(s) for PDB: 4ZZ0
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:In situ inhibition of GRAFTase in human KB cells assessed as incorporation of [14C]-glycine into [14C]-formyl GAR preincubated for 30 mins followed b...More data for this Ligand-Target Pair
3D Structure (crystal)TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 99nMpH: 7.5Assay Description:GARFTase activity was determined by measuring the rate of 5,8-dideazatetrahydrofolate production in the presence of varying concentrations of antifol...More data for this Ligand-Target Pair