Report error Found 12 Enz. Inhib. hit(s) for PDB: 5CEH
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5A (unknown origin) using H3K4me3 as substrate by MSD ELISA analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5A (unknown origin ) by HTMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/20 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/20 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 506nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+3nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as increase in H3K4me3 levels preincubated for 4 days measured up to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+3nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as increase in H3K4me3 levels preincubated for 4 days measured up to 24 hrs by ELISAMore data for this Ligand-Target Pair