Report error Found 17 Enz. Inhib. hit(s) for PDB: 5D1J
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged CDK2/cyclinA1 expressed in baculovirus infected Sf9 insect cells using FRET-labeled...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of South Australia Cancer Research Institute
Curated by ChEMBL
University of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human CDK2 after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of C-terminal His6-tagged human full length CDK2/cyclin A expressed in Sf21 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human full length C-terminal His6-tagged CDK2/N-terminal GST-tagged cyclin A expressed in baculovirus infected Sf21 insect cells using ...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of CDK2/cyclin A by IMAP florescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of CDK2/Cyclin A by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of South Australia Cancer Research Institute
Curated by ChEMBL
University of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged CDK2/N-terminal GST-tagged cyclin E expressed in baculovirus infected Sf21 insect ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of South Australia Cancer Research Institute
Curated by ChEMBL
University of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 48nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of South Australia Cancer Research Institute
Curated by ChEMBL
University of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of CDK2/cyclinE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of full-length human CDK2/N-terminal GST-tagged Cyclin A2 (1 to 432 residues) expressed in Baculovirus expression system using FAM-P8/P18 ...More data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for full-length CDK2More data for this Ligand-Target Pair