Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 5EZV
LigandPNGBDBM50242401(A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...)
Affinity DataEC50:  390nMAssay Description:Activation of human AMPK alpha2/beta1/gamma1 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50242401(A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...)
Affinity DataKd:  510nMAssay Description:Binding affinity to human recombinant N-terminal AVI-tagged phosphorylated AMPK alpha1beta1gamma1 expressed in Escherichia coli BL21 cells after 1 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50242401(A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...)
Affinity DataKd:  1.45E+4nMAssay Description:Binding affinity to human recombinant N-terminal AVI-tagged phosphorylated AMPK alpha1beta2gamma1 expressed in Escherichia coli BL21 cells after 1 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50242401(A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...)
Affinity DataEC50:  800nMAssay Description:Activation of human AMPK alpha1/beta1/gamma1 expressed in baculovirus/Sf9 cells using SAMS peptide as substrate incubated for 15 mins by in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50242401(A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...)
Affinity DataKd:  487nMAssay Description:Binding affinity for full length human N-terminal His/BAP-tagged AMPK alpha1/beta1/gamma1 expressed in Escherichia coli BL21-CodonPlus by surface pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)