Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5FC4
LigandPNGBDBM50160001(CHEMBL3785892 | US10093640, Example 52 | US1084403...)
Affinity DataKi:  200nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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PDB3D3D Structure (crystal)
LigandPNGBDBM50160001(CHEMBL3785892 | US10093640, Example 52 | US1084403...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM50160001(CHEMBL3785892 | US10093640, Example 52 | US1084403...)
Affinity DataKi:  231nMAssay Description:Displacement of FITC-Bak-BH3 peptide probe from N-terminal His-tagged human Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21(DE3) after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)